Boronic acid, B-(2-ethoxy-4,5-difluorophenyl)-

Boronic acid, B-(2-ethoxy-4,5-difluorophenyl)- - Names and Identifiers

Name	(2-ethoxy-4,5-difluorophenyl)boronic acid
Synonyms	4,5-Difluro-2-ethoxyphenylboronic acid (2-ETHOXY-4,5-DIFLUOROPHENYL)BORONIC ACID (2-ethoxy-4,5-difluorophenyl)boronic acid Boronic acid, B-(2-ethoxy-4,5-difluorophenyl)-
CAS	870778-87-3
InChI	InChI=1/C8H9BF2O3/c1-2-14-8-4-7(11)6(10)3-5(8)9(12)13/h3-4,12-13H,2H2,1H3

Boronic acid, B-(2-ethoxy-4,5-difluorophenyl)- - Physico-chemical Properties

Molecular Formula	C8H9BF2O3
Molar Mass	201.96
Density	1.29g/cm³
Melting Point	136-140°C
Boling Point	324.6°C at 760 mmHg
Flash Point	150.1°C
Vapor Presure	9.91E-05mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.484

Boronic acid, B-(2-ethoxy-4,5-difluorophenyl)- - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

Boronic acid, B-(2-ethoxy-4,5-difluorophenyl)- - Introduction

(2-ethoxy-4,5-difluorophenyl)boronic acid is an organic compound with the chemical formula C8H9BF2O3. It is a white to slightly yellow crystalline powder with a special odor.

This compound is mainly used in the field of organic synthesis. It is an important organic boron reagent, which can be used in organic synthesis reactions such as phenyl reaction, coupling reaction and reduction reaction. It can be used as an intermediate of drugs and chemicals for the preparation of potential drug molecules.

The common method for preparing (2-ethoxy-4,5-difluorophenyl)boronic acid is by reacting 4,5-difluorophenyl boronic acid and ethanol. The experimental conditions are generally at room temperature under alkaline conditions for several hours, and the product is obtained by crystallization and filtration.

This compound has limited safety information. It is irritating to the eyes and skin and may cause allergic effects. Use personal protective equipment such as safety glasses, gloves and protective clothing. Avoid inhaling dust or contact with skin. In the process of operation to ensure good ventilation conditions. If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 02:00:48